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Name: Iwao Ojima
Title: Distinguished Professor of Chemistry and Director of ICB&DD
Arthur C. Cope Scholar
Date & Place of Birth: June 5, l945,
|
Education: |
1968 B. S. degree The University of Tokyo |
l973-l983 Senior Research Fellow and
Group Leader, Sagami Institute of Chemical Research
1983 Associate Professor, Department of Chemistry, State University of New York
at Stony Brook
1984 Professor, Department of Chemistry, State University of New York at Stony
Brook
1989 Professeur invité, Université Claude Bernard Lyon I, Lyon, France
1991 Leading Professor, Department of Chemistry, State University of New York
at Stony Brook
1995 Distinguished Professor, Department of Chemistry, State University of New
York at Stony Brook
1996 Visiting Professor, The University of Tokyo, Tokyo, Japan
1997 Visiting Professor, The Scripps Research Institute, La Jolla, CA
1997 Professeur invité, Université de Paris XI,
BIOCIS, Châtenay-Malabry, France
1997-2003 Chairman, Department of Chemistry, State University of New York at
Stony Brook
2003 Director, Institute of Chemical Biology and Drug Discovery, Stony Brook.
(Awards)
· The
25th National Young Investigator Award ("Shimpo Sho"), The Chemical Society of
· Arthur
C. Cope Scholar Award, the American Chemical Society, 1994.
· The
51st Chemical Society of Japan Award (“Nihon Kagaku Kai Sho”) for distinguished achievements, The
Chemical Society of Japan, 1999.
· Emanuel
B. Hershberg Award for Important Discoveries in
Medicinally Active Substances, the American Chemical Society, 2001.
· Outstanding
Inventor Award, The Research Foundation of the
· NYSTAR Faculty
Development Award,
(Other Honors)
· Fellow,
John Simon Guggenheim Memorial Foundation, 1995.
· Fellow,
American Association for the Advancement of Science, 1997.
· Fellow,
· American Chemical Society, Medicinal
Chemistry Hall of Fame, 2006.
· William
and
· Leading
Professorship,
· Distinguished
Professorship,
· He was
invited by the Royal Swedish Academy of Sciences to serve as a nominator for
the Nobel prize in chemistry for the
years 1990, 1996, 2002.
· Eli
Lilly Lecturer,
· National
Science Council Lecturer,
· J.
Clarence Karcher Lecturer, The
· George
Lesher Lecturer, Rensselaer Polytechnic Institute,
1995.
· Boehringer-Ingelheim Distinguished Lecturer,
· Weissberger-Williams
Lecturer, Eastman Kodak Co., 1997
· Dr.
H. Martin Friedman University Lecturer, Rutgers,
· Bristol-Meyers
Squibb Distinguished Lecturer,
· FMC
Discovery Chemistry Lecturer, FMC Corporation, 2003
· J. Clarence
Karcher Lecturer, The
· Guest Editor, “Drug Resistant
Tuberculosis: A Challenge in Chemotherapy”, Curr. Topics Med. Chem., 2006
· Guest Editor, “Modern Molecular
Approaches to Drug Discovery”, Acc.
Chem. Res., 2007
· Negishi-Brown
Lecturer,
· Guest Editor, “Modern Natural
Products Chemistry in Drug Discovery”, J. Med. Chem., 2007
(Advisory Board)
1. Editorial Advisory Board of Journal of
Molecular Catalysis (1986-1995)
2. Editorial Advisory Board of Journal of
Organic Chemistry (ACS) (1995-1999)
3. Editorial Advisory Board of Organometallics (ACS)
(1996-1998)
4. Editorial Advisory Board of Current Topics in Medicinal Chemistry (2002-)
5. Editorial Advisory Board of Letters in Drug Design & Discovery (2003-)
6. Editorial Advisory Board of Medicinal
Chemistry (2004-)
7. Editorial Advisory Board of Chemistry
Letters (2005-)
8. Editorial
Advisory Board of Anti-Cancer Agents in
Medicinal Chemistry (2006-)
9. Basic Science Advisory Board member, Cancer
Institute for
(Symposia and
Conferences)
1. Chairperson, The Stony Brook Symposium on Taxol and Taxotère, "
2. Chairperson, Symposium on "Recent
Advances in the Chemistry of Taxane and Taxoid Anticancer Agents", 207th American Chemical
Society National Meeting,
3. Chairperson, Symposium on "Fluoroamino Acids and Peptides in Medicinal
Chemistry", 210th American Chemical Society National Meeting,
4. Organizer and Chairperson, Symposium on
"New Prospects in Anticancer Agents for the 21st Century" 219th
American Chemical Society National Meeting, San Francisco, March (2000).
5. Organizer, Ernest Guenther Award
Symposium”, the 219th American Chemical Society National Meeting,
6. Organizer, Ernest Guenther Award Symposium,
the 229th American Chemical Society National Meeting,
7. Organizer, Symposium on “Drug
Resistant Tuberculosis – Challenge in Chemotherapy”, the 229th American
Chemical Society National Meeting,
8. Organizer,
ACS Award in Organometallic
Chemistry Symposium, the 231st American Chemical Society National Meeting,
9.
Editorial Advisory Board of Anti-Cancer Agents in Medicinal Chemistry (2006-)Organizer,
“Ernest Guenther Award Symposium, the 233rd American Chemical
Society National Meeting,
10. Organizer,
“Modern Molecular Strategies for Tumor-Targeting Drug Dilivery”,
the 234th American Chemical Society National Meeting,
(Advisory
Committee, Panel Reviewer)
1. Advisory Committee Member, NIH, Medicinal Chemistry (MCHA)
Study Section (1988-1992).
2. Ad Hoc Member, Triennial Oversight Committee,
Chemistry Division, NSF (1992).
3. Panel Reviewer, Basic Energy Science
4. Advisory Committee Member Reserve, NIH (1992-1995).
5. Panel Reviewer, REU
Program, Chemistry Division, NSF (1992).
6. Panel Reviewer, NSF Postdoctoral Fellowship
in Chemistry (1994).
7. Chemistry and Related Sciences Special
Emphasis Panel, NIH, Bioorganic and Natural Product
Chemistry (BNP-1) Program (1995).
8. Special Panel Reviewer, NIH,
Medicinal Chemistry (MCHA) Study Section (1995).
9. Chemistry and Related Sciences Special
Emphasis Panel, NIH, Bioorganic and Natural Product
Chemistry (BNP-1) Program (1996).
10. Chemistry and Related Sciences Special
Emphasis Panel, NIH, SBIR
and STTR Programs (1996).
11. Panel Reviewer, NSF Small Business
Innovation Research (SBIR) Program (1997).
12. Special Panel Reviewer, NIH,
Medicinal Chemistry (MCHA) Study Section (1998).
13. Special Panel Reviewer, NIH,
Medicinal Chemistry (MCHA) Study Section (2001).
14. Special Panel Reviewer, NIH,
Bioorganic and Natural Product Chemistry (BNP) Study
Section (2002).
15. Panel Reviewer, NCI, Basic & Preclinical
Subcommittee IRG (2002).
16. Panel Reviewer, NCI, Basic & Preclinical
Subcommittee IRG (2003).
17. Panel Reviewer, NIH,
Drug Discovery & Molecular Pharmacology (DMP)
Study Section, Oncological Sciences IRG (2004).
18. Panel Reviewer, NCI, National
Cooperative Drug Discovery Groups for Cancer (NCDDG) IRG (2004).
19. Special Emphasis Panel Reviewer, NCI, ONC-K Study Section (2005).
20. Special Emphasis Panel Reviewer, NIH, BCMB-B Study Section (2005).
(American
Chemical Society)
1. Executive Committee Member, Division of
Organic Chemistry, American Chemical Society (1998-2001).
2.
He has served as a consultant
for E. I. du Pont, Eli Lilly, Air Products &
Chemicals, Mitsubishi Chem. Ind., Nippon
Steel Corp. Life Science Division, Rhone-Poulenc
Rorer, ImmunoGen, Inc., Taiho
Pharmaceutical Co., Milliken & Co., Aventis Pharma, OSI Pharmaceuticals,
Inc., Ajinomoto Co., Inc. (current), INDENA, SpA (current), Central Glass Co. (current), Mitsubishi
Chem. Corp. (current).
He is a member of
American Chemical Society, American Association for the Advancement of Science,
American Association for Cancer Research, American Peptide Society, New York
Academy of Sciences, Sigma Xi, The Chemical Society of Japan, and The Society
of Synthetic Organic Chemistry,
His research interests include drug
design and discovery (anticancer agents, antibacterial agents, enzyme
inhibitors, antithrombotic agents), medicinal
chemistry and chemical biology, catalytic asymmetric synthesis, organic
synthesis by means of organometallic reagents and
catalysts, homogeneous catalysis and organometallic
chemistry, peptide and peptidomimetics, b-lactam chemistry, and organofluorine
chemistry (fluoroamino acids and peptides, medicinal
applications). He has published more
than 360 papers and reviews in leading journals and more than l50 patents and
patent applications, edited 6 books, and he has given 84 Plenary and Invited Lectures in international
conferences and symposia by October 2007.
SciFinder list more than 650 publications to
his credit. He has also given more than 100 invited lectures at universities,
research institutes, and industries in the last 5 years (total >440 since
his move to Stony Brook in 1983).
63. F&F International Seminar on “Prospects in Finechemicals, Pharmaceuticals, and Fluoromaterials”,
[M. Harada, Organizer],
64. International Symposium on Pharmaceuticals and Intermediates
[T,-P. Lin, Organizer],
65. Gordon
Research Conference on Heterocyclic Chemistry [
66. 43th American
Society of Pharmacognosy Annual Meeting [Robert P. Borris, Organizer],
67. .17th Annual William S.
Johnson Symposium in Organic Chemistry [Organizers: C. Khosla, B. M. Trost, P. A. Wender],
68. The 2003 “Visions in Chemistry” Symposium [T. R. Nieduzak, Chairman], American Chemical Society, North Jersey Section and Avenits, Ratitan, NJ, May 14, 2003. “Chemistry and Chemical Biology of New Generation Taxoid Anticancer Agents”.
69. Bürgenstock
International Symposium on “Fluorine in Life Sciences” [M.
Schlosser, Chairman],
70. Symposium on “Fluorinated Synthons” [V. Soloshonok,
V. A. Petrov, Chairpersons], September 7-9, 2003, 226th American
Chemical Society National Meeting,
71. 13
European Symposium on Organic Chemistry [V. Sunjic, Chairman],
72. The
19th Pesticide Science Society of
73. Pharmaceutical
Sciences World Congress
(PSWC2004) [Y. Sugiyama, Chairman],
74. Ischia Advanced
75. 17th
International Symposium on Fluorine Chemistry,
76. ACS Symposium on “Current Frontiers of Fluoroorganic Chemistry” [V. Soloshonok;
K. Mikami, Organizers], 230 American Chemical Society
National Meeting,
77. NATO Science Advanced Study
Institute “New Methodologies and Techniques in Organic Chemistry:
Sustainable Development in a Secure Environment”,
78.
79. Pacifichem 2005 Conference,
80. The 4th Congress of
International Drug Discovery Science and Technology (IDDST-2006),
81. 7th
All-Russian Conference, “Fluorine Chemistry”,
82. The 2nd
International Conference on Joint Project of Chemical Synthesis Core Research
Institutions, “Development of New Synthetic Methods and Creation of
Functions”,
83. The 2nd
Negishi-Brown Lectures,
84. New
England ACS Medicinal Chemistry Symposium,
85. First
International Conference on Drug Design and Discovery,
86. Swiss
Chemical Society, Medicinal Chemistry Division Mini-Symposium on Drug
Targeting,
Invited
Lectures Since 2002:
384. OSI Pharmaceuticals, Inc.,
385. Pfizer, Inc.
386. Kyowa Hakko Kogyo. Co., Pharmaceutical Research Institute,
387. F&F International Seminar,
388. Taiho Pharmaceutical Co. Ltd.,
389. Shanghai Institute of Organic Chemistry,
390. Bristol-Myers Squibb,
391. Northeastern Medicinal Chemistry and Pharmacognosy
Symposium (NERMCAP XXVII),
392. Colorado State University, Fort Collins, CO [10/4/02, Profs. T. Rovis, R. M. Williams, A. I. Meyers]
393. Central Glass Co.,
394. The
395. Ajinomoto Co., Inc., Pharmaceutical Research Institute [10/16/02,
Dr. T. Tsuji]
396. Mitsubishi Chemical Corporation,
397. Kitasato Institute, Shirokane,
398. FMC Corporation,
399. “Suri no Tsubasa”
Summer Seminar,
400. Ruder Boskovic Institute,
401. Mitsubishi Chemical Group Science and
402. Central Glass, Co.,
403.
404. The
405. Ajinomoto Co., Inc., Pharmaceutical Research
Laboratories,
406.
407. The
408. Purdue Pharma,
L.P.,
409. Kaneka Chem. Ind., Bioscience Research
Institute, Takasago,
410.
411.
412. F&F International Seminar,
413. The Kitasato
Institute, Shirogane,
414. The
415. Synta Pharmaceuticals, Inc.,
416.
Università del Piemonte Orientale, Faculty of Pharmacy,
Novara, Italy [9/13/04, Prof. G. Appendino]
417.
418.
419.
420. Central Glass,
421. Ajinomoto Co., Inc., Pharmaceutical Research
Institute,
422. Mitsubishi Chemical Group, Science and
Technology Research Center, Inc., Organic Synthesis and Molecular Catalysis
Laboratory,
423. Mitsubishi Pharma
Corp., Discovery Research Laboratory,
424. The
425. Luitpold Pharmaceuticals, Inc.,
426. American Biosciences, Inc.
427. Kitasato Institute of Life Sciences, Graduate School
of Infection Control Sciences, Shirogane, Tokyo,
Japan [7/19/05, Prof. S. Omura].
428.
429. Shanghai
430. Pharmaceutical
Research Institute, Ajinomoto Co., Inc.,
431. Chemical
Research Laboratory, Central Glass Co.,
432. Science
and Technology Center, Mitsubishi Chemical Group,
433. The
434.
435. Honeycomb Worldwide, Inc., Web Seminar [Ms. D. Pe, April 7, 2006].
436. Schering-Plough
Research Institute,
437. Cytokinetics, Inc.,
438. Science
and Technology Center, Mitsubishi Chemical Group,
439. The University of Tokyo, Graduate School of Chemistry, Hongo, Tokyo, Japan [Prof. E. Nakamura, Nov. 1, 2006]
440. Pharmaceutical
Research Institute, Ajinomoto Co., Inc.,
441. Chemical
Research Laboratory, Central Glass Co.,
442. Kitasato Institute and
443. Sepracor Pharmaceuticals, Inc.,
444.
1.
Iwao Ojima, "Catalytic
Asymmetric Synthesis", VCH Publishers,
2.
G. I. Georg, T. Chen,
3.
I. Ojima,
J. McCarthy, and J. T. Welch (Eds.), "Biomedical Frontiers of Fluorine
Chemistry", ACS Symp.
Series 639; The American Chemical Society,
4.
Iwao Ojima, "Catalytic
Asymmetric Synthesis, Second Edition", John Wiley & Sons,