Dr. Ioana Ungureanu


Education
                    

1997-2000            PhD in organic chemistry (University Louis Pasteur, Strasbourg)

1995-1998             Student at École Normale Supérieure, Paris

1997-1998             Diplôme d’Études Approfondies - (equivalent to MSc) in Pharmacology and  Pharmacochemistry, (University Louis Pasteur, Strasbourg)

1996-1997             Diplôme d’Études Approfondies in Organic Chemistry, (University Paris V-   Ren?Descartes, Paris)

1995-1996            Maîtrise (equivalent to BSc) in Organic and Biological Chemistry (University  Paris VI-Pierre et Marie Curie, Paris)

1992-1995            Student in chemistry at the University of Timisoara (Romania)


Research Experience


2000- 2003:

 Postdoctoral fellow, State University of New York at Stony Brook

1997-2000   

 Reactivity of Phenylaziridines and Phenylazetidines and their Applications to the  Synthesis of Biologically Active Compounds (under the supervision of Dr. Andr?Mann)

1996-1997  

Synthesis of Taxol Prodrugs (under the supervision of Dr Claude Monneret,   Institut Curie, Paris)

July 1996 

Snthesis of Nitrogen Mustards Prodrugs (Institut Curie, Paris)


Publications

 

"2-Phenyl-N-tosylazetidine as a formal 1,4 dipole precursor" Ioana Ungureanu , Philippe Klotz , Angèle Schoenfelder and Andr?Mann Chem. Commun., 2001, 11, 958 - 959 

"Cancer Chemotherapy: A Paclitaxel Prodrug for ADEPT (Antibody-Directed Enzyme Prodrug Therapy)" Frédéric Schmidt, Ioana Ungureanu, Romain Duval, Alain Pompon, Claude Monneret, Eur. J. Org. Chem., 2001, 11, 2129-2134

"Phenylaziridine as a Masked 1,3 Dipole in Reactions with Nonactivated Alkenes" Ioana Ungureanu, Philippe Klotz, Andr?Mann, Angewandte Chem. 2000, 39, 4615-4617

“Phenylaziridine as 1,3-Dipole. Applications to the Synthesis of Functionalized Pyrrolidines?Ioana Ungureanu, Cristian Bologa, Said Chayer, Andr?Mann Tetrahedron Letters, 1999 40, 5315-5318

“From Phenylaziridine to Phenylkainoids. A formal Synthesis of (?-Phenylkainic Acid?/b> Marie-Reine Schneider, Philippe Klotz, Ioana Ungureanu, Andr? Mann* and Camille-Georges Wermuth, Tetrahedron letters, 1999 40, 3873-3876

“Antibody Directed Enzyme Prodrug Therapy: Syntesis and Biological Evaluation of a Paclitaxel Prodrug?Romain Duval, Ioana Ungureanu, Frédéric Schmidt, Claude Monneret, Poster at "The Fourteenth French-Japanese Symposium on Medicinal and Fine Chemistry" (FJS-99), 19-22 September 1999, La Baule, France

“Short Access to Phenyl-kainoid Acids by Phenylaziridine Ring Opening With Allylsilane? Philippe Klotz, Marie-Reine Schneider, Ioana Ungureanu, Andr?Mann.  Poster at The 10-th IUPAC Symposium of Organometallic Chemistry Directed Towards Organic Synthesis (OMCOS), 18-22 July 1999, Versailles, France (Prize for the best poster of the session)

“From Phenylaziridine to Phenylkainoid Acids?/b> Marie-Reine Schneider, Philippe Klotz, Ioana Ungureanu, Andr?Mann. Poster at ?/b>The Impact of Organic Synthesis on Drug Discovery ? September 6-8, 1998, University of Heidelberg, Germany

“New Reactions of Phenylaziridines?Ioana Ungureanu, Andr?Mann and Camille-Georges Wermuth-oral communication at The French Chemical Society Meeting-Strasbourg, January 11-12, 1999

 


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